microRNAs (miRNAs) are small noncoding RNAs that are important post-transcriptional regulators of gene expression.miRNAs can induce thresholds in protein synthesis.Such thresholds in protein output can be also achieved by oligomerization of transcription factors (TF) for the control of gene expression.First, Magnetic Power Bank we propose a minimal
Loss of dysferlin (DYSF) protein in humans results in limb-girdle muscular dystrophy 2B, characterized by progressive loss of muscles in the distal limbs with impaired locomotion.The DYSF-null (Bla/J) mouse develops severe steatotic muscles upon aging.Here, we report a marked increase in adipocytes, especially in the psoas and gluteus muscles but n
Mild traumatic brain injuries (mTBIs) are prevalent worldwide.mTBIs can impair hippocampal-based functions such as memory and cause network hyperexcitability of the dentate gyrus (DG), a key entry point to hippocampal circuitry.One candidate for mediating mTBI-induced hippocampal cognitive and physiological dysfunction is injury-induced changes in